Formulation and characterization of ketoprofen embedded polycaprolactone microspheres using solvent evaporation method
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چکیده
منابع مشابه
Formulation and characterization of ketoprofen embedded polycaprolactone microspheres using solvent evaporation method
The purpose of this study was to prepare polymeric microspheres containing Ketoprofen (KFN) by single emulsion [oil-in-water (o/w)] solvent evaporation method. Polycaprolactone (PCL), biocompatible polymer, was used for the preparation of sustained released microspheres of KFN. A Plackett–Burman design was employed by using the Design-Expert® software (Version9.0.3.1, Stat-Ease Inc., Minneapoli...
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متن کاملDevelopment and Characterization of Controlled Release Ketoprofen Microspheres
Microspheres ketoprofen (KP) were prepared by o/w emulsion solvent evaporation technique using EudragitRS100 as a polymeric material. The effect of process variables such as drug: polymer ratio, stirring rate, emulsifier concentration, internal organic solvent and dispersing medium volumes were examined. The prepared formulations were characterized for particle size distribution, percent yield,...
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ژورنال
عنوان ژورنال: ADMET & DMPK
سال: 2015
ISSN: 1848-7718
DOI: 10.5599/admet.3.2.167